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UNC926

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    UNC926
  • UNC926
Cat No: 27302
Biochemicals - Small Molecule Inhibitors
Cayman

UNC926 is an antagonist of the MBT domain-containing methyl-lysine reader proteins L3MBTL1, L3MBTL3, and L3MBTL4.{48422} It inhibits methyl-lysine histone peptide substrate binding of L3MBTL1, L3MBTL3, and L3MBTL4 (IC50s =3.9, 3.2, and 15.6 μM, respec...

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This product can only be bought through Cayman Chemical. Please contact us.

Territorial Availability: Available through Bertin Technologies only in France
Synonyms:
  • (3-bromophenyl)[4-(1-pyrrolidinyl)-1-piperidinyl]-methanone
Correlated keywords:
  • 1782573-49-2 1581296-53-8 UNC 926 L3MBT L1 L3 L4 MB TL1 Tl3 TL4 MBTD 1 SFMBT CBX 7
Product Overview:
UNC926 is an antagonist of the MBT domain-containing methyl-lysine reader proteins L3MBTL1, L3MBTL3, and L3MBTL4.{48422} It inhibits methyl-lysine histone peptide substrate binding of L3MBTL1, L3MBTL3, and L3MBTL4 (IC50s =3.9, 3.2, and 15.6 μM, respectively) selectively over MBT domain-containing MBTD1 and SFMBT1 and chromo domain-containing CBX7 (IC50s = >30 μM).
Size 5 mg
Shipping dry ice
CAS Number 1184136-10-4
Molecular Formula C16H21BrN2O
SMILES BrC1=CC=CC(C(N2CCC(N3CCCC3)CC2)=O)=C1
Molecular Weight 337,3
Formulation A crystalline solid
Purity ≥98%
Custom Code 2933.39
UNSPSC code 12352100

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.

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Cross selling for this product : UNC926 There are 5 products.

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