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13,14-dihydro-15-keto Prostaglandin F ELISA Kit

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    13,14-<wbr/>dihydro-<wbr/>15-<wbr/>keto Prostaglandin F<sub>2α</sub> ELISA Kit
  • 13,14-<wbr/>dihydro-<wbr/>15-<wbr/>keto Prostaglandin F<sub>2α</sub> ELISA Kit
Cat No: 516671
Assay Kits - Elisa
Cayman
€356.00
Price is excluding VAT and does not include packaging neither shipping

Prostaglandin F2α (PGF2α) is one of the five primary prostaglandins derived enzymatically directly from the endoperoxide PGH2. PGF2α was initially discovered in seminal fluid, and to date the majority of the functional roles ascribed to it relate to f...

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This product can only be bought through Cayman Chemical. Please contact us.

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Territorial Availability: Available through Bertin Technologies only in Europe
Technical Warning: Check the Additional Items Required section of this kit booklet to verify if UltraPure Water (Milli-Q or equivalent) is needed for this assay
Correlated keywords:
  • solid plates metabolites EIAs enzyme immunoassays kits measures ELISAs 13,14-dh-15-k-PGF2.alpha. 13,14-dihydro-15-keto-PGF2.alpha. 13,14-dh-15-k-PGF2alpha 13,14-dihydro-15-keto-PGF2alpha 13,14-dh-15-k-prostaglandins 13,14-dihydro-15-keto-prostaglandins prostaglandins assays
Product Overview:
Prostaglandin F2α (PGF2α) is one of the five primary prostaglandins derived enzymatically directly from the endoperoxide PGH2. PGF2α was initially discovered in seminal fluid, and to date the majority of the functional roles ascribed to it relate to fertility, pregnancy, and parturition. PGF2α is a potent luteolytic agent and is used to induce ovulation in domestic livestock. It is also a potent uterine stimulant, and is part of the cascade of myometrial stimulants which induce and sustain labor. PGF2α is rapidly metabolized to 13,14-dihydro-15-keto PGF2α in vivo, by the enzymes 15-hydroxy prostaglandin dehydrogenase and Δ13-reductucase.{310,1157,5442,387} Measurement of 13,14-dihydro-15-keto PGF2α in plasma can be used as a marker of the in vivo production of PGF2α.{878,1463} The Cayman Chemical 13,14-dihydro-15-keto PGF2α Enzyme Immunoassay is a competitive assay that provides measurements of 13,14-dihydro-15-keto PGF2α within the range of 2.3-5,000 pg/ml, typically with a detection limit (80% B/B0) of approximately 15 pg/ml. Although the tracer and antiserum for this assay have been sold separately for many years, the reagents are now combined with an accurate standard and packaged together in a convenient assay kit. The assay has been validated for the measurement of 13,14-dihydro-15-keto PGF2α in plasma, a common matrix for measurement of this PGF2α metabolite.{878}
Size 96 solid wells
Shipping dry ice
Stability Store at -20 degrees; shelf life 180 days
Custom Code 3822.00
UNSPSC code 41116104

Del Vecchio, R.P., Maxey, K.M., and Lewis, G.S. A quantitative solid-phase enzymeimmunoassay for 13,14-dihydro-15-keto-prostaglandin F in plasma. Prostaglandins 43 321-330 (1992).

Keirse, M.J.N.C., and Turnbull,

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Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

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ISO Guide 34:2009

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