Ornidazole

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Ornidazole

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Cat No: 26818

Ornidazole is an orally bioavailable 5-nitroimidazole derivative with antibacterial and antiprotozoal activities.{35717,26702} Ornidazole inhibits the growth of clinical isolates of B. fragilis (MICs = 0.5-5 μM) and various anaerobic bacteria when use...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

?-(chloromethyl)-2-methyl-5-nitro-1H-imidazole-1-ethanol

Correlated keywords:

95880-34-5 166734-79-8 anti-bacterial protozoal nitro imidazole Bacteroides Trichomoniasis Tritrichomonas Entamoeba Dazolic Giro Madelen NSC95075 Ornidal Ornidone Ornilox Ornisid Ornitop Ro70207 Ro7 70207 tiberal

Product Overview:
Ornidazole is an orally bioavailable 5-nitroimidazole derivative with antibacterial and antiprotozoal activities.{35717,26702} Ornidazole inhibits the growth of clinical isolates of B. fragilis (MICs = 0.5-5 μM) and various anaerobic bacteria when used at concentrations ranging from less than 0.1 to 3.2 μg/ml.{26702,48267} It also inhibits the growth of Giardia isolates (IC50s = 0.01-0.47 μg/ml).{48268} Oral administration of ornidazole reduces T. vaginalis and T. foetus infection in mice and E. histolytica infection in rats with curative dose (CD50) values of 37, 3, and 10 mg/kg, respectively.{35717} Ornidazole (400 mg/kg per day) induces infertility in male rats within 7 days and inhibits spermatozoa binding to rat oocyte zona pellucida.{48269,48270}

Size	5 g
Shipping	dry ice
CAS Number	16773-42-5
Molecular Formula	C₇H₁₀ClN₃O₃
SMILES	OC(CCl)CN1C(C)=NC=C1[N+]([O-])=O
Molecular Weight	219,6
Formulation	A crystalline solid
Purity	≥98%
Custom Code	2933.29
UNSPSC code	12352100

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.