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Fexofenadine-d10 (hydrochloride)

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    Fexofenadine-<wbr/>d<sub>10</sub> (hydro<wbr/>chloride)
  • Fexofenadine-<wbr/>d<sub>10</sub> (hydro<wbr/>chloride)
Cat No: 26115
Biochemicals - Isotopically Labeled Standards
Cayman

Fexofenadine-d10 is intended for use as an internal standard for the quantification of fexofenadine (Item No. 18191) by GC- or LC-MS. Fexofenadine is a histamine H1 receptor antagonist (Ki = 10 nM).{27483} It reverses contraction of isolated rat trach...

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: 1 mg

This product can only be bought through Cayman Chemical. Please contact us.

Territorial Availability: Available through Bertin Technologies only in France
Synonyms:
  • 4-[1-hydroxy-4-[4-(hydroxydiphenylmethyl-d10)-1-piperidinyl]butyl]-?,?-dimethyl-benzeneacetic acid, monohydrochloride
Correlated keywords:
  • 1215900-18-7 deuterated deuterium GCMS LCMS H-1 IL8 TNFa HCT-116 COLO205 alernex allegra fastofen feksine fexadyne fexo fexodine fexofen MDL 16455A MDL16455A rapido telfast BD vivafeks
Product Overview:
Fexofenadine-d10 is intended for use as an internal standard for the quantification of fexofenadine (Item No. 18191) by GC- or LC-MS. Fexofenadine is a histamine H1 receptor antagonist (Ki = 10 nM).{27483} It reverses contraction of isolated rat tracheal strips induced by acetyl-β-methylcholine (Item No. 23092).{36897} Fexofenadine inhibits expression of IL-8 in TNF-α-stimulated HCT116 and COLO 205 cells.{36898} Oral administration of fexofenadine (2 and 10 mg/kg) reduces severity of colitis and phospho-IκB kinase activation in a mouse model of colitis induced by dextran sulfate sodium (DSS; Item No. 23250).
Size 1 mg
Shipping dry ice
CAS Number 1215821-44-5
Molecular Formula C32H29D10NO4 • HCl
SMILES OC(C1=C([2H])C([2H])=C([2H])C([2H])=C1[2H])(C2=C([2H])C([2H])=C([2H])C([2H])=C2[2H])C3CCN(CCCC(O)C4=CC=C(C(C)(C)C(O)=O)C=C4)CC3.Cl
Molecular Weight 548,2
Formulation A solid
Purity ≥99% deuterated forms (d1-d10)
Custom Code 3822.19
UNSPSC code 12352100

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.

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