23-epi-26-Deoxyactein

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23-epi-26-Deoxyactein

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Cat No: 25126

Biochemicals - Natural Products

23-epi-26-Deoxyactein is a triterpene glycoside and a major constituent of black cohosh (C. racemosa).{43486,43487} It reduces intracellular calcium concentrations, collapse of the mitochondrial membrane potential, production of reactive oxygen specie...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

(3?,12?,16?,23S,24R,25R)-12-(acetyloxy)-16,23:23,26:24,25-triepoxy-9,19-cyclolanostan-3-yl, ?-D-xylopyranoside

Correlated keywords:

158050-31-8 302335-32-6 310878-76-3 1140532-53-1 Caulerpa MC3T3E1 IL1? RINm5F ?cells

Product Overview:
23-epi-26-Deoxyactein is a triterpene glycoside and a major constituent of black cohosh (C. racemosa).{43486,43487} It reduces intracellular calcium concentrations, collapse of the mitochondrial membrane potential, production of reactive oxygen species (ROS), and cardiolipin peroxidation and inhibits autophagy and apoptosis in osteoblastic MC3T3-E1 cells induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD).{43486} 23-epi-26-Deoxyactein (0.01-10 μM) reduces production of ROS and IL-1β and cell death induced by methylglyoxal in RIN-m5F β-cells.{43487}

Size	500 µg
Shipping	dry ice
CAS Number	264624-38-6
Molecular Formula	C₃₇H₅₆O₁₀
SMILES	C[C@](CO1)(O2)[C@@H]2[C@@]31O[C@@]4([H])C[C@@]5(C)[C@]6([H])CC[C@]7([H])[C@]8(CC[C@H](O[C@]9([H])OC[C@@H](O)[C@H](O)[C@H]9O)C7(C)C)[C@]6(C8)C[C@@H](OC(C)=O)[C@]5(C)[C@@]4([H])[C@H](C)C3
Molecular Weight	660,8
Formulation	A crystalline solid
Purity	≥95%
Custom Code	2910.90
UNSPSC code	12352100

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Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

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Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.