Somatostatin-28 (human, mouse, r

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Somatostatin-28 (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt)

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Cat No: 24991

Biochemicals - Peptides

Somatostatin-28 is a cyclic neuropeptide hormone that has a role in endocrine regulation.{42021} It is a somatostatin (SST) receptor agonist that binds to SST1, SST2, SST3, SST4, and SST5 (IC50s = 0.60, 0.12, 0.22, 0.83, and 0.41 nM, respectively, in ...

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Territorial Availability: Available through Bertin Technologies only in France

Correlated keywords:

75141-79-6 SS-28 SS28 GHIH GHRIH SRIF-28 SRIF28 SRIH SST-1 2 3 4 5 CCL-39 neuro-peptide 73032-94-7

Product Overview:
Somatostatin-28 is a cyclic neuropeptide hormone that has a role in endocrine regulation.{42021} It is a somatostatin (SST) receptor agonist that binds to SST1, SST2, SST3, SST4, and SST5 (IC50s = 0.60, 0.12, 0.22, 0.83, and 0.41 nM, respectively, in CCL39 cells expressing human recombinant receptors).{42022} It inhibits cAMP accumulation induced by forskolin (Item No. 11018) in CCL39 cells expressing human recombinant SST1, SST2, SST3, SST4, and SST5 (EC50s = 5.13, 1.91, 6.46, 2.95, and 3.55 nM, respectively).{42023} Somatostatin-28 stimulates growth hormone (GH) release from primary porcine pituitary cells when used at a concentration of 1 fM.{42024} It inhibits acid secretion induced by gastrin I (Item No. 24457) and IBMX (Item No. 13347) in isolated rat gastric mucosa (EC50s = 27 and 252 nM, respectively).{42025} In vivo, somatostatin-28 dose-dependently increases basal and pentagastrin-induced gastric acid secretion in rats.{42026}

Size	500 µg
Shipping	dry ice
Molecular Formula	C₁₃₇H₂₀₇N₄₁O₃₉S₃ • XCF₃COOH
SMILES	[H]N[C@@H](CO)C(N[C@H](C(N[C@@H](CC(N)=O)C(N[C@@H](CO)C(N[C@@H](CC(N)=O)C(N1CCC[C@H]1C(N[C@H](C(N[C@H](C(N[C@H](C(N2CCC[C@H]2C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCCN)C(N[C@H](C(NCC(N[C@H](C(N[C@@H](CCCCN)C(N[C@@H](CC(N)
Molecular Weight	3148,6
Formulation	A lyophilized powder
Purity	≥95%
Custom Code	3504.00
UNSPSC code	12352100

Technical File

MSDS

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.