Methocarbamol

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Methocarbamol

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Cat No: 23870

Biochemicals - Small Molecule Inhibitors

Methocarbamol is an orally bioavailable skeletal muscle relaxant.{38705} In vivo, methocarbamol inhibits the ability of mice to remain on a vertical ladder for 1 minute (ED50 = 15 mg/kg) and decreases forelimb grip strength by 35.9% when administered ...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

3-(2-methoxyphenoxy)-1,2-propanediol, 1-carbamate

Correlated keywords:

145308-03-8 AHR85 Avetil Delaxin Etroflex Glycerylguaiacolate Lumirelax Miolaxene NSC170960 Neuraxin Reflexyn Relestrid Robamol Robaxin Robinax Surquetil Traumacut Tresortil guaiamar CA-II

Product Overview:
Methocarbamol is an orally bioavailable skeletal muscle relaxant.{38705} In vivo, methocarbamol inhibits the ability of mice to remain on a vertical ladder for 1 minute (ED50 = 15 mg/kg) and decreases forelimb grip strength by 35.9% when administered at a dose of 500 mg/kg.{38705,38707} It abolishes femoral nerve-stimulated polysynaptic reflex contractions of the cat tibialis anterior muscle and prolongs the mean refractory period of directly or indirectly stimulated skeletal muscle when administered at a dose of 200 mg/kg.{38708} Methocarbamol also selectively inhibits human carbonic anhydrase (CA) isoform I over CAII (IC50s = 70 and ~80,000 μM, respectively).{38706} Formulations containing methocarbamol have been used to treat skeletal muscle spasms.

Size	5 g
Shipping	wet ice
CAS Number	532-03-6
Molecular Formula	C₁₁H₁₅NO₅
SMILES	COC1=C(OCC(O)COC(N)=O)C=CC=C1
Molecular Weight	241,2
Formulation	A crystalline solid
Purity	≥98%
Custom Code	2924.29
UNSPSC code	12352100

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MSDS

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

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ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.