Methylhomatropine (bromide)

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Cat No: 23832

Biochemicals - More Biochemicals

Methylhomatropine is an anticholinergic agent.{36327} It blocks spasm of rat and rabbit intestines induced by acetylcholine (Item No. 23829) ex vivo (ED50s = 0.052 and 0.011 mg/kg, respectively). Methylhomatropine slows intestinal transit of a charcoa...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

(3-endo)-3-[(2-hydroxy-2-phenylacetyl)oxy]-8,8-dimethyl-8-azoniabicyclo[3.2.1]octane, monobromide

Correlated keywords:

31610-86-3 42522-67-8 55198-66-8 58725-74-9 1786394-41-9 methylbromide arkitropin camatropine esopin helbatropin homapin homatrocel homatromide homatropil homatropine methylbromide homolone malcotran mesopin methatropin methatropine methylhomatropinium NSC34399 novatrin novatrine novatropin novatropine sed-tems sethyl tropinium mandelate anti-cholinergic methobromide

Product Overview:
Methylhomatropine is an anticholinergic agent.{36327} It blocks spasm of rat and rabbit intestines induced by acetylcholine (Item No. 23829) ex vivo (ED50s = 0.052 and 0.011 mg/kg, respectively). Methylhomatropine slows intestinal transit of a charcoal meal in rats (ED50 = 27 mg/kg) and blocks salivary gland secretion in rabbits (ED50 = 0.16 mg/kg). It also induces mydriasis in mice when administered subcutaneously or orally (ED50s = 0.13 and 12 mg/kg, respectively). Formulations containing methylhomatropine have been used in the treatment of nausea, vomiting, and motion sickness.

Size	1 g
Shipping	dry ice
CAS Number	80-49-9
Molecular Formula	C₁₇H₂₄NO₃ • Br
SMILES	O=C(C(O)C1=CC=CC=C1)O[C@H]2C[C@H]3CC[C@H]([N+]3(C)C)C2.[Br-]
Molecular Weight	370,3
Formulation	A crystalline solid
Purity	≥98%
Custom Code	2922.19
UNSPSC code	12352100

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

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ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.