PCSK9 (human) Monoclonal Antibody (Clone 15A6)
PCSK9 (human) Monoclonal Antibody (Clone 15A6)
Proprotein convertase subtilisin kexin 9 (PCSK9) is a member of the subtilisin serine protease family with an important role in...
From €454.00 – €1,464.00
Enzyme ImmunoAssay (EIA) is a technique to detect and quantify antigens (proteins, hormones…) or antibodies in samples. It relies on the ability of an antibody to bind a specific antigen. Either the antibody or the antigen is labelled with an enzyme whose substrate is a chromogen or a fluorogen converted in a measurable product (color or fluorescence).|Enzyme-linked Immunosorbent Assay (ELISA) is a type of EIA using a solid phase (ex: microtiter plate) coated with an antigen immobilizing the molecule to detect. Over the time, scientists have extended the term ELISA to EIAs using an antibody coating the solid phase. That explains why our EIA kits using coated antibodies are also called ELISA kits.|Insulin is a polypeptide hormone with molecular weight of 6,000 Daltons, composed of two peptides chains, A and B, jointed by two cross-linked disulphide bonds and synthesised by the beta cells of the islets of Langherans of the pancreas. Insulin influences most of the metabolic functions of the body. Its best known action is to lower the blood glucose concentration by increasing the rate at which glucose is converted to glycogen in the liver and muscles and to fat in adipose tissue, by stimulating the rate of glucose metabolism and by depressing gluconeogenesis. Focus on hemolysis: Hemolysis interferes with the assay by degrading insulin. To prevent hemolysis consequences, SPI-BIO has an inhibitor cocktail and a procedure available.
Territorial Availability: Available worldwide directly through Bertin or your local distributor
Technical Warning: Check the Additional Items Required section of this kit booklet to verify if UltraPure Water (Milli-Q or equivalent) is needed for this assay
Size | 480 wells, 96 wells |
---|---|
Shipping | dry ice |
Tracer | AcetylCholinesterase AChE |
Custom code | 3822000000 |
Specificity | Hamster Insulin: 100%, Human insulin 100, Mouse Insulin: 100%, Porcine Insulin: 100%, Rat Insulin: 100%, Sheep Insulin: 100% |
Application media | No extraction required; inhibitor cocktail to prevent hemolysis consequences, Plasma and serum |
Sample volume | 50 µL |
Detection limit | |
Standard Curve Range | 0.08-10 ng/mL |
UNSPSC code | 41116104 |
Proprotein convertase subtilisin kexin 9 (PCSK9) is a member of the subtilisin serine protease family with an important role in...
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