Confirm delete?

Bertin Bioreagent
logo

Search

Contact Us

STAT-8-Isoprostane ELISA Kit

  • Zoom
    STAT-<wbr/>8-<wbr/>Isoprostane ELISA Kit
  • STAT-<wbr/>8-<wbr/>Isoprostane ELISA Kit
Cat No: 500431
Assays - Other Eia Kits
Cayman
€308.00
Price is excluding VAT and does not include packaging neither shipping

Cayman’s STAT-8-isoprostane ELISA is a competitive assay that permits the rapid measurement of 8-iso PGF2α from biological samples, requiring only 1 hour incubation and development times for each step. This assay format is similar to that employed in C...

More

This product can only be bought through Cayman Chemical. Please contact us.

- +
Territorial Availability: Available through Bertin Technologies only in Europe
Technical Warning: Check the Additional Items Required section of this kit booklet to verify if UltraPure Water (Milli-Q or equivalent) is needed for this assay
Product Overview:
Cayman’s STAT-8-isoprostane ELISA is a competitive assay that permits the rapid measurement of 8-iso PGF2α from biological samples, requiring only 1 hour incubation and development times for each step. This assay format is similar to that employed in Cayman’s original 8-isoprostane ELISA (Item No. 516351) with the only change being the use of an alkaline phosphatase tracer in place of an AChE tracer. While Item No. 516351 offers superior sensitivity (IC50 = ~35 pg/ml), the STAT-8-isoprostane assay offers the convenience of a fast assay while still achieving an IC50 value of 180 pg/ml and a detection limit (80% B/B0) of approximately 45 pg/ml.
The isoprostanes are a family of eicosanoids of non-enzymatic origin produced by the random oxidation of tissue phospholipids by oxygen radicals. At least one of the isoprostanes, 8-isoprostane (8-iso PGF2α), has biological activity and has implicated as a causative mediator and specific marker of free radical-induced damage in a variety of diseases related to oxidative stress. Cayman Chemical's STAT-8-isoprostane ELISA is a competitive assay that permits the rapid measurement of 8-iso PGF2α from biological samples, requiring only 1 hour incubation and development times for each step. This assay format is the similar to that employed in Cayman's popular 8-isoprostane ELISA (Item No. 516351) with the only change being the use of an alkaline phosphatase tracer in place of an AChE tracer. While Item No. 516351 offers superior sensitivity (IC50 ~35 pg/ml), the new STAT-8-isoprostane Assay offers the convenience of a fast assay while still achieving an IC50 of 180 pg/ml and a detection limit (80% B/B0) of approximately 45 pg/ml.
Size: 96 strip wells
Shipping: wet ice
Stability: Store at -20 degrees; shelf life 365 days maximum after production
Custom Code: 3822000002
UNSPSC code: 41116104
UN Number: UN1170

Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.

/ We also advise you

Cross selling for this product : STAT-<wbr/>8-<wbr/>Isoprostane ELISA Kit There are 8 products.