Confirm delete?

Bertin Bioreagent
logo

Search

Contact Us

HDAC1 Polyclonal Antibody

  • Zoom
    HDAC1 Polyclonal Antibody
  • HDAC1 Polyclonal Antibody
Cat No: 13491
Polyclonal&monoclonal Antibody - Miscellaneous Antibodies
Cayman
€310.00
Price is excluding VAT and does not include packaging neither shipping

Antigen: synthetic peptides corresponding to amino acids 1-5, 433-448 and 467-482 of human HDAC1 • Host: rabbit • Cross-Reactivity: (+) human HDAC1 • Application(s): WB
Histone deacetylase (HDAC) and histone acetyltransferase (HAT) are enzymes that r...

More
: 1 ea

This product can only be bought through Cayman Chemical. Please contact us.

- +
Territorial Availability: Available through Bertin Technologies only in Europe
Product Overview:
Antigen: synthetic peptides corresponding to amino acids 1-5, 433-448 and 467-482 of human HDAC1 • Host: rabbit • Cross-Reactivity: (+) human HDAC1 • Application(s): WB
Histone deacetylase (HDAC) and histone acetyltransferase (HAT) are enzymes that regulate transcription by selectively deacetylating or acetylating the ε-amino groups of lysines located near the amino termini of core histone proteins. Eleven members of HDAC family have been identified in the past several years. These HDAC family members are divided into two classes, I and II. HDAC1 is a Class I HDAC which is related to the yeast HDAC Rpd3. It is primarily localized to the nucleus with ubiquitous distribution throughout human cell lines and tissues. By modifying chromatin structure and other non-histone proteins, HDACs play important roles in controlling complex biological events, including cell development, differentiation, programmed cell death, angiogenesis, and inflammation. Considering these major roles, it is conceivable that dysregulation of HDACs and subsequent imbalance of acetylation and deacetylation may be involved in the pathogenesis of various diseases, including cancer and inflammatory diseases.
Size: 1 ea
Shipping: wet ice
Stability: Store at -20 degrees; shelf life 365 days maximum after production
Host: rabbit
Antigen: synthetic peptides corresponding to amino acids 1-5, 433-448 and 467-482 of human HDAC1
Application(s):

WB

Specificity:
Formulation: 100 µg of protein G-purified IgG in 200 µl PBS containing 0.02% sodium azide
Custom Code: 3822000002
UNSPSC code: 12352203

Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.

/ We also advise you

Cross selling for this product : HDAC1 Polyclonal Antibody There are 8 products.