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15-keto Fluprostenol isopropyl ester

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    15-<wbr/>keto Fluprostenol isopropyl ester
  • 15-<wbr/>keto Fluprostenol isopropyl ester
Cat No: 16786
Chemicals - Prostaglandin/leukotriene/ Thromboxane
Cayman
€94.00
Price is excluding VAT and does not include packaging neither shipping

A potential metabolite of travoprost when administered to animals
Travoprost is an F-series prostaglandin analog which has been approved for use as an ocular hypotensive drug. Oxidation of the C-15 hydroxyl group without isopropyl ester hydrolysis pro...

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Territorial Availability: Available through Bertin Technologies only in Europe
Product Overview:
A potential metabolite of travoprost when administered to animals
Travoprost is an F-series prostaglandin analog which has been approved for use as an ocular hypotensive drug. Oxidation of the C-15 hydroxyl group without isopropyl ester hydrolysis produces 15-keto fluprostenol isopropyl ester (15-keto travoprost). 15-keto Travoprost is a potential metabolite of travoprost when administered to intact animals. 15-keto Travoprost is also one of the common minor impurities found in commercial preparations of the bulk drug compound. In general, F-series prostaglandin analogs with a 15-keto functional group lose a great deal of their FP receptor binding affinity, but retain enough to show a continued weak IOP hypotensive response. The efficacy of 15-keto travoprost as an ocular hypotensive has not been established.
Size: 1 mg
Shipping: wet ice
Stability: Store at -20 degrees; shelf life 730 days maximum after production
CAS Number: 404830-45-1
Molecular Formula: C26H33F3O6
SMILES: O[C@@H]1[C@H](C/C=C\CCCC(OC(C)C)=O)[C@@H](/C=C/C(COC2=CC(C(F)(F)F)=CC=C2)=O)[C@H](O)C1
Molecular Weight: 498.5
Formulation: A solution in methyl acetate
Purity: ≥98%
Custom Code: 2937500000
UNSPSC code: 12352100
UN Number: UN1231

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