8-bromo-Cyclic AMP (sodium salt)

Biochemicals - Small Molecule Activators

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Cat No: 14431

Biochemicals - Small Molecule Activators

8-bromo-Cyclic AMP (8-bromo-cAMP) is a cell-permeable analog of cAMP that activates cyclic-AMP-dependent protein kinase with a Ka value of 0.05 μM.{22886} It activates cyclic-GMP-dependent protein kinase with 100-fold reduced potency (Ka = 5.8 μM).{2...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

8-bromo-cyclic 3',5'-(hydrogen phosphate)-adenosine, monosodium salt

Correlated keywords:

23583-48-4 c-AMP GMP HL60 PAR 2 SLIGRLNH2 NSC 171719 NSC171719

Product Overview:
8-bromo-Cyclic AMP (8-bromo-cAMP) is a cell-permeable analog of cAMP that activates cyclic-AMP-dependent protein kinase with a Ka value of 0.05 μM.{22886} It activates cyclic-GMP-dependent protein kinase with 100-fold reduced potency (Ka = 5.8 μM).{22886} 8-bromo-cAMP is more stable to hydrolysis and has increased membrane permeability compared to unmodified cAMP.{22886}

Size	5 mg
Shipping	dry ice
CAS Number	76939-46-3
Molecular Formula	C₁₀H₁₀BrN₅O₆P • Na
SMILES	O[C@H]1[C@H](N2C(Br)=NC3=C2N=CN=C3N)O[C@H]4[C@H]1OP(OC4)([O-])=O.[Na+]
Molecular Weight	430,1
Formulation	A crystalline solid
Purity	≥95%
Custom Code	2903.94
UNSPSC code	12352100

Technical File

MSDS

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